Vitamin B12
Methylcobalamin
An essential water-soluble vitamin critical for nervous system function, red blood cell formation, and DNA synthesis. Methylcobalamin is the naturally active form, directly usable by the body without conversion.
What the Research Shows
Delpre et al. (1999)
Oral methylcobalamin (1,000 mcg/day) was as effective as intramuscular injection for correcting B12 deficiency.
British Journal of Clinical Pharmacology
Health et al. (2015)
B12 deficiency was associated with 2.5× higher risk of cognitive decline over a 10-year period in elderly populations.
Neurology
Oberley (2002)
Methylcobalamin preferentially distributes to nervous tissue and showed regenerative effects on damaged peripheral nerves.
Alternative Medicine Review
How It Works
Vitamin B12 acts as a co-factor for methionine synthase (converting homocysteine to methionine, essential for DNA methylation) and L-methylmalonyl-CoA mutase (critical for myelin synthesis and energy metabolism in the Krebs cycle). Methylcobalamin specifically supports neuronal health by promoting myelin sheath repair and nerve regeneration. It also enables proper red blood cell maturation, preventing megaloblastic anaemia.
Recommended Dosage
Clinical Range
1,000–2,000 mcg/day of methylcobalamin
In Kodlas Zero Products
1,000 mcg per serving in VitaProPlus
Found In
⚠️ Medical Disclaimer
This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Clinical studies are referenced for informational context — individual results may vary. Always consult a qualified healthcare professional before starting any supplement.