Ashwagandha (KSM-66®)
Withania somnifera
A premier adaptogenic herb used in Ayurvedic medicine for over 3,000 years. KSM-66® is the most clinically studied ashwagandha extract, standardised to 5% withanolides using a unique aqueous extraction process.
What the Research Shows
Chandrasekhar et al. (2012)
60-day RCT showed KSM-66 reduced serum cortisol by 27.9% and significantly improved stress-related quality of life scores.
Indian Journal of Psychological Medicine
Wankhede et al. (2015)
8-week trial demonstrated ashwagandha supplementation increased muscle strength, reduced body fat, and raised testosterone levels in men.
Journal of the International Society of Sports Nutrition
Lopresti et al. (2019)
Ashwagandha (240 mg/day) significantly reduced anxiety symptoms (HAM-A scores) with a calming effect comparable to some medications.
Medicine (Baltimore)
How It Works
Ashwagandha modulates the hypothalamic-pituitary-adrenal (HPA) axis, reducing cortisol output under chronic stress. It also enhances GABA-mimetic activity for calming effects, supports thyroid hormone production (T3/T4), and increases mitochondrial enzyme activity for sustained energy. KSM-66® has additional demonstrated benefits for testosterone levels and exercise performance in men.
Recommended Dosage
Clinical Range
250–600 mg/day of root extract (5% withanolides)
In Kodlas Zero Products
250 mg per serving in VitaProPlus
Found In
⚠️ Medical Disclaimer
This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Clinical studies are referenced for informational context — individual results may vary. Always consult a qualified healthcare professional before starting any supplement.