MSM
Methylsulfonylmethane
An organic sulphur compound found naturally in plants, animals, and humans. MSM provides bioavailable sulphur essential for collagen and keratin production.
What the Research Shows
Kim et al. (2006)
12-week RCT of 50 patients showed MSM (3g/day) significantly reduced pain and improved physical function.
Osteoarthritis and Cartilage
Debbi et al. (2011)
MSM (1.125g twice daily) significantly improved WOMAC pain and function scores over 12 weeks.
BMC Complementary and Alternative Medicine
Butawan et al. Review (2017)
Comprehensive review confirmed MSM's anti-inflammatory, antioxidant, and analgesic properties across multiple trials.
Nutrients
How It Works
MSM donates sulphur for the formation of disulphide bonds in collagen, the primary structural protein in cartilage, tendons, and ligaments. It also acts as a mild analgesic and anti-inflammatory by inhibiting NF-κB signalling and reducing pro-inflammatory cytokines like IL-6 and TNF-α in joint tissue.
Recommended Dosage
Clinical Range
1,000–3,000 mg/day
In Kodlas Zero Products
1,000 mg per serving in FlexiCorPlus
Found In
⚠️ Medical Disclaimer
This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Clinical studies are referenced for informational context — individual results may vary. Always consult a qualified healthcare professional before starting any supplement.